Cyclobenzaprine: Side Effects, dosage, uses, and more

The elderly may also be more at risk for CNS adverse events such as hallucinations and confusion, cardiac events resulting in falls or other sequelae, drug-drug and drug-disease interactions. For these reasons, in the elderly, cyclobenzaprine should be used only if clearly needed. In such patients FLEXERIL should be initiated with a 5 mg dose and titrated slowly upward.

In light of these findings, therapy with FLEXERIL in the elderly should be initiated with a 5 mg dose and titrated slowly upward. In the higher dose groups this microscopic change was seen after 26 weeks and even earlier in rats which died prior to 26 weeks; at lower doses, the change was not seen until after 26 weeks. For most patients, the recommended dose of Flexeril is 5 mg three times a day. It is available in immediate-release tabletsof 5 milligrams, 7.5 milligrams, and 10 milligrams and extended-release capsules of 15 milligrams and 30 milligrams and is usually given three times daily.

Talk with your doctor about other drug options that may work for you. Many insurance companies require prior authorization for this drug. This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription. During pregnancy, this medication should be used only when clearly needed.

• Therefore, before using this product, tell your doctor or pharmacist of all the products you use.
• It’s also be effective in treating low back pain, neck pain, and fibromyalgia.
• It works by inhibiting serotonin transmission at the spinal cord (3).
• Prolonged use can lead to increased tolerance and physical dependence.

Flexeril is a prescription medication used to relax muscles and relieve pain due to muscle spasms. Flexeril belongs to a class of drugs called muscle relaxants, which help by preventing muscle spasms without affecting overall muscle control and function. Drug interactions may change how flexeril and thc your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist.

What is Flexeril?

It is not known whether this drug is excreted in human milk. Less frequent dosing should be considered for hepatically impaired or elderly patients (see PRECAUTIONS, Impaired Hepatic Function, and Use in the Elderly). Our Flexeril (cyclobenzaprine) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

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Cyclobenzaprine did not demonstrate mutagenic activity in the male mouse at dose levels of up to 20 times the human dose. Some medicines can interact with cyclobenzaprine and cause a serious condition called serotonin syndrome. Ask your doctor before making any changes in how or when you take your medications.

Carcinogenesis, Mutagenesis, Impairment of Fertility

Based on individual patient response, the dose may be increased to 10 mg three times a day. Use of FLEXERIL for periods longer than two or three weeks is not recommended. In order to protect against the rare but potentially critical manifestations described above, obtain an ECG and immediately initiate cardiac monitoring.

Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first. Antispastic medications are effective in treating spasticity, but high doses can lead to unwanted side effects. Other treatments can help with spasticity as well, including physical therapy and Botox® injections. Flexeril is the brand name for a muscle relaxant called cyclobenzaprine (1). Other brands of cyclobenzaprine include Fexmid, FusePaq Tabradol, and Amrix (an extended-release capsule).

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Cyclobenzaprine HCl relieves skeletal muscle spasm of local origin without interfering with muscle function. It is ineffective in muscle spasm due to central nervous system disease. Using Flexeril with other drugs that make you drowsy can worsen this effect.

All RxWiki content including health news, medication pages, and condition pages published prior to February 2023, was written and maintained by on-staff pharmacists. Please be advised that this content is no longer actively maintained and may now contain outdated information. If you have any questions regarding previously published content, please contact Do not drive or operate machinery until you know how Flexeril affects you.